|  
       Learning Modules 
     | 
  ||
|  
       Closes Tuesday, 4 September 2018 (Monday is Labor Day)  | 
  ||
| Submodule 1A | Getting Started in Blackboard | |
| Submodule 1B | Getting to know you | |
| Submodule 1C | Introduction to Toxicology; "Highly Toxic" | |
| Submodule 1D | Dose units | |
| Submodule 1E | Biology, just a little | |
| Submodule 1F | Chemistry, just a little | |
| Learning Goals | ||
| Closure | ||
|  
       | 
  ||
 
      Module 02 | 
     
       Closes Monday, 10 September  | 
  |
| Submodule 2A | Death in the Laboratory; MSDS; | |
| Submodule 2B | Organic Chemistry, just a little | |
| Submodule 2C | Biochemistry, just a little | |
| Submodule 2D | Tissues, Organs, Systems, Signals and Receptors. | |
| Submodule 2E | Kinetics, Introduction, Absorption. | |
| Learning Goals | ||
| Closure | ||
| Closes Monday, 17 September, S&B Chapter 4 | ||
|  
       Submodule 3A 
     | 
    Cellular Sites of Action | |
|  
       Submodule 3B 
     | 
    Nerve gas | |
|  
       Submodule 3C 
     | 
    More kinetics. | |
|  
       Submodule 3D 
     | 
    MSDS Project | |
|  
       Submodule 3E 
     | 
    Web searching. | |
| Learning Goals | ||
| Closure | ||
| Closes Monday, 24 September, S&B Chapters 3 and 6 | ||
|  
       Submodule 4A 
     | 
    Biotransformation, S&B Chapter 3 (lightly) | |
|  
       Submodule 4B 
     | 
    Scientific Literature | |
|  
       Submodule 4C 
     | 
    Cancer I, the science, S&B Chapter 6 | |
|  
       Submodule 4D 
     | 
    Paper | |
|  
       Submodule 4E 
     | 
    UAF Library | |
| Learning Goals | ||
| Closure | ||
| Closes Monday, 1 October MSDS Project Due. | ||
|  
       Submodule 5A 
     | 
    LD50s, Reference Doses (non-cancer) | |
|  
       Submodule 5B 
     | 
    Epidemiology (Cancer and non-cancer) | |
|  
       Submodule 5C 
     | 
    In vitro genotoxicity tests, Ames and others | |
|  
       Submodule 5D 
     | 
    Animal 
      models, Low dose extrapolations; Weight of Evidence Classification  | 
  |
|  
       Submodule 5E 
     | 
    Ames Paper | |
| Learning Goals | ||
| Closure | ||
| Closes Monday, 8 October. Paper Topics Due. | ||
|  
       Submodule 6A 
     | 
    Reproductive Toxicology, S&B Chapter 7 | |
|  
       Submodule 6B 
     | 
    Examples | |
|  
       Submodule 6C 
     | 
    Respiratory Toxicology, S&B Chapter 8 | |
|  
       Submodule 6D 
     | 
    Asbestos and particulates | |
|  
       Submodule 6E 
     | 
    Resources: IRIS, ASTDR, | |
| Learning Goals | ||
| Closure | ||
| Closes Monday, 15 October (Discussion due 24 October) | ||
|  
       Submodule 7A 
     | 
    Cardiovascular Toxicology S&B Chapter 9 | |
|  
       Submodule 7B 
     | 
    Neurotoxicology, S&B Chapter 10 | |
|  
       Submodule 7C 
     | 
    Benzene metabolism | |
|  
       Submodule 7D 
     | 
    Free Radicals | |
| Learning Goals | ||
| Closure | ||
| Closes 22 October | ||
|  
       Submodule 8A 
     | 
    Hepatic Toxicology, S&B Chapter 11 | |
|  
       Submodule8B 
     | 
    Alcohol | |
|  
       Submodule 8C 
     | 
    Renal Toxicology, S&B Chapter 12 | |
|  
       Submodule 8D 
     | 
    Risk Communications and Ethics | |
| Learning Goals | ||
| Closure | ||
| Closes 29 October Paper outline and Lit search due. | ||
|  
       Submodule 9A 
     | 
    Immunotoxicology, S&B Chapter 13 | |
|  
       Submodule 9B 
     | 
    Hormonally Active Agents (aka Endocrine Disrupters) | |
|  
       Submodule 9C 
     | 
    Mixtures | |
|  
       Submodule 9D 
     | 
    Metals | |
| Learning Goals | ||
| Closure | ||
 
      Module 10 | 
    Closes 5 November | |
| Submodule 10A | Specific Agents: Pesticides | |
| Submodule 10B | Specific Agents: Solvents and hydrocarbons | |
| Submodule 10C | Radiation, just a little | |
| Submodule 10D | Plant and animal toxins | |
| Learning Goals | ||
| Closure | ||
 
      Module 11 | 
    Closes 12 November | |
| Submodule 11A | Toxics from the Environment (S & B Chapters 14, 17.) | |
| Submodule 11B | Risk Assessment, 8A from ENVE 649, and 8B | |
| Submodule 11C | Ecological Risk Assessment 8C (Chapter 14) | |
| Learning Goals | ||
| Closure | ||
Module 13 | 
    Placeholder. Thanksgiving week. Work on Paper | |
| Closes 26 November | ||
|  
       Submodule 12A 
     | 
    Regulatory toxicology | |
|  
       Submodule 12B 
     | 
    Lists | |
| Learning Goals | ||
| Closure | ||
|  
       | 
    ||
| Closes 3 December, PAPER DUE, Final Exam Out | ||
| Billion Dollar Baby Powder | ||
| Mass Murder | ||
| Precaution | ||
| Food and Fads | ||
| Petroleum | ||
| Clusters | ||
| Forest Fire Smoke | ||
| PBPK Models | ||
 
      Module 15 | 
    Closes 10 December, Final Exam Due | |