Ecological Risk Assessment
"...no adverse effect on human health or the environment." is the 
  mandate of several environmental laws. From 8B you have a good grasp on the 
  basics of human health risk assessment. From that base we will talk a little 
  about adverse effects on the environment. Here are the main differences between 
  the two types of risk assessment:

Let's discuss each:
  - You realize by now that our estimation of low dose effect on humans is at 
    least one step removed from science for most chemicals, although it is the 
    best we can do. In any given meso-environment or ecosystem there are hundreds 
    or thousand of species, from whales to microorganisms. It is rare we know 
    anything about the toxicity of any particular chemical to more than one or 
    two of these species. If there is a species that is both convenient and relevant, 
    it could be tested, just like Cheeech 
    did to the fish back in Submodule 
    1E. By convenient I mean amenable to laboratory testing. Relevant means 
    important to the ecosystem in question, recognized by the public, sensitive 
    to the chemical. These are often impractical to find, so standard indicator 
    species are used. These you order from a supply house and they are delivered 
    in a day or two. Then they are tested with standard EPA protocols. As for 
    human dose-response estimates, the indicator species are about the best you 
    can do, given normal limitations of time and budget. The resulting dose-response 
    numbers may or may not be relevant.
 
  - For human receptors, we do not want to hurt anybody. Now or ever. For animals 
    in an ecosystem, we can accept some mortality, as long as the population stays 
    healthy. On a macroscale, the Fish and Game Department manages game populations 
    this way. For example, while for humans a one in one million or one in ten 
    thousand chance of harm is acceptable to some. (Note this is computed harm, 
    it may not hurt anyone.) For damage to an ecosystem, a LD10 might be acceptable. 
    That is, it will kill 10% of the animal species population. As long as the 
    PRP ("Potentially Responsible Party, i.e., the polluter) can demonstrate 
    the population will spring back in a year or two, an LD 50 might be acceptable.
 
  - For humans we sometimes separate male and females. We always separate children. 
    But that's about it. For ecosystems we must consider trophic levels, i.e., 
    the food chain. Ducks eat lead shot from the bottom of the lake, foxes eat 
    the ducks. Some contaminants increase as they are passed up the food chain
 
  - Effects are impossible to test in humans, but often can be tested in at 
    least some animals.
 
  - Pathways. We looked at some pathways for human receptors a few pages 
    back . The next page has the approximate equivalent for an Ecorisk site.
 
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